Bilal Mir | 1dfg

Dr. Heidi Noels and Dr. Yvonne Döring receive the W.H. Hauss Award from the DGAF

19-21 April 2018

Dr. Heidi Noels from the Institute for Molecular Cardiovascular Research at RWTH Aachen University together with Dr. Yvonne Döring from the Institute for Prophylaxis and Epidemiology of Circulatory Diseases at LMU Munich together received the DGAF W.H. Hauss Award 2018 from the German Society for Atherosclerosis Research (DGAF) during the 32nd Annual Meeting of the DGAF in Rauischholzhausen, Germany. They were awarded for their publication "Vascular CXCR4 Limits Atherosclerosis by Maintaining Arterial Integrity: Evidence From Mouse and Human Studies." (Circulation. 2017; 136: 388-403). In this work it could be shown that vascular CXCR4 has an atheroprotective function by maintaining the arterial integrity and preserving the endothelial barrier function. In addition, CXCR4 stabilizes a contractile smooth muscle cell phenotype. Targeted enhancement of these CXCR4-mediated protective functions could open up novel therapeutic options in the treatment of atherosclerosis.

The award was sponsored by a long-standing active member of the DGAF, Prof. Dr. Winfried März.

Project area Z

Administrative project

Robert Werner Mertens

MD student

University Hospital RWTH Aachen

Department of Internal Medicine

Project: The role of incretin hormone GLP-2 in septic cardiomyopathy

PI: Michael Lehrke

Robert Werner Mertens

MD student

University Hospital RWTH Aachen

Department of Internal Medicine

Project: The role of incretin hormone GLP-2 in septic cardiomyopathy

PI: Michael Lehrke

Consortium

Summerschool 2018

Winterschool 2020

Winterschool 2019

Winterschool 2020

Winterschool 2019

Winterschool 2020

Winterschool 2019

Summerschool 2018

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Mechanisms of Cardiovascular Complications in Chronic Kidney Disease

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PhD MD TRR219-associated students

Bilal Mir

PhD student

University Hospital RWTH Aachen

Department of Cardiology, Medical Clinic I

Project: The role of endolysosomal maturation on the calcification potential of vascular smooth muscle cell-derived extracellular vesicles

PI: Claudia Goettsch

Calcifying extracellular vesicles (EVs) are the smallest unit involved in the formation of arterial microcalcification. In this project, we investigate the role of endolysosomal maturation on the release and cargo loading of calcifying EVs

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