PhD MD TRR219-associated students
University Hospital RWTH Aachen
Institute for Molecular Cardiovascular Research
Project: Post-translational modifications of HDL in CKD patients
PI: Vera Jankowski / In co-operation with Prof. Dr. Thimoteus Speer (Saarland University Hospital, Homburg/Saar)
Patients with chronic kidney disease have a markedly elevated cardiovascular mortality risk. HDL can be rendered dysfunctional by protein modifications.
The aim of this project is to identify post-translational modifications of HDL in CKD patients by mass spectrometric analyses and to examine their pathophysiological effects.