Dr. Heidi Noels and Dr. Yvonne Döring receive the W.H. Hauss Award from the DGAF
19-21 April 2018
Dr. Heidi Noels from the Institute for Molecular Cardiovascular Research at RWTH Aachen University together with Dr. Yvonne Döring from the Institute for Prophylaxis and Epidemiology of Circulatory Diseases at LMU Munich together received the DGAF W.H. Hauss Award 2018 from the German Society for Atherosclerosis Research (DGAF) during the 32nd Annual Meeting of the DGAF in Rauischholzhausen, Germany. They were awarded for their publication "Vascular CXCR4 Limits Atherosclerosis by Maintaining Arterial Integrity: Evidence From Mouse and Human Studies." (Circulation. 2017; 136: 388-403). In this work it could be shown that vascular CXCR4 has an atheroprotective function by maintaining the arterial integrity and preserving the endothelial barrier function. In addition, CXCR4 stabilizes a contractile smooth muscle cell phenotype. Targeted enhancement of these CXCR4-mediated protective functions could open up novel therapeutic options in the treatment of atherosclerosis.
The award was sponsored by a long-standing active member of the DGAF, Prof. Dr. Winfried März.
Project area Z
Administrative project
Robert Werner Mertens
MD student
University Hospital RWTH Aachen
Department of Internal Medicine
Project: The role of incretin hormone GLP-2 in septic cardiomyopathy
PI: Michael Lehrke
Robert Werner Mertens
MD student
University Hospital RWTH Aachen
Department of Internal Medicine
Project: The role of incretin hormone GLP-2 in septic cardiomyopathy
PI: Michael Lehrke
Consortium
Mechanisms of Cardiovascular Complications
in Chronic Kidney Disease
The SFB/TRR219 is supported by the German Research Foundation (DFG)
Project-ID 322900939
Publications
Qinxue Sun, Maike Baues, Barbara M Klinkhammer, Josef Ehling, Sonja Djudjaj, Natascha I Drude, Christoph Daniel, Kerstin Amann, Rafael Kramann, Hyojin Kim, Julio Saez-Rodriguez, Ralf Weiskirchen, David C Onthank, Rene M Botnar, Fabian Kiessling, Jurgen Floege, Twan Lammers, Peter Boor
Elastin imaging enables noninvasive staging and treatment monitoring of kidney fibrosis
Science Translational Medicine
Marieke Sternkopf, Sven Thoroe-Boveleth, Tobias Beck, Kirsten Oleschko, Ansgar Erlenkotter, Ulrich Tschulena, Sonja Steppan, Thimoteus Speer, Claudia Goettsch, Vera Jankowski, Joachim Jankowski, Heidi Noels, Eutox European Uremic Toxin Work Group
A Bifunctional Adsorber Particle for the Removal of Hydrophobic Uremic Toxins from Whole Blood of Renal Failure Patients
Toxins (Basel)
Stefan J Schunk, Alexander Zarbock, Melanie Meersch, Mira Kullmar, John A Kellum, David Schmit, Martina Wagner, Sarah Triem, Stefan Wagenpfeil, Hermann-Josef Grone, Hans-Joachim Schafers, Danilo Fliser, Thimoteus Speer, Stephen Zewinger
Association between urinary dickkopf-3, acute kidney injury, and subsequent loss of kidney function in patients undergoing cardiac surgery: an observational cohort study
The Lancet
Felix Mahfoud, Michael Böhm, Roland Schmieder, Krzysztof Narkiewicz, Sebastian Ewen, Luis Ruilope, Markus Schlaich, Bryan Williams, Martin Fahy and Giuseppe Mancia
Effects of renal denervation on kidney function and long-term outcomes: 3-year follow-up from the Global SYMPLICITY Registry.
European Heart Journal
Sean S. Scholz, Markus Dillmann, Alexander Flohr, Christina Backes, Tobias Fehlmann, Dominic Millenaar, Christian Ukena, Michael Böhm, Andreas Keller, Felix Mahfoud
Contemporary scientometric analyses using a novel web application: the science performance evaluation (SciPE) approach.
Clinical Research in Cardiology