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IRTG Journal Club



Andrea Bonnin- Marquez

González-López et al. (2023)

“Role of miR-15a-5p and miR-199a-3p in the inflammatory pathway regulated by NF-κB in experimental and human

​Clin Transl Med. 2023 Aug;13(8):e1363. doi: 10.1002/ctm2.1363.



Andrea Gorgels

Blaser et al. (2023)

„Multiomics of Tissue Extracellular Vesicles Identifies Unique Modulators of Atherosclerosis and Calcific Aortic Valve Stenosis.”

Circulation. 2023 Aug 22;148(8):661-678. doi: 10.1161/CIRCULATIONAHA.122.063402. Epub 2023 Jul 10.



Anna Leitz

Rana et al. (2024)

“Glomerular-tubular crosstalk via cold shock Y-box binding protein-1 in the kidney.”

Kidney Int. 2024 Jan;105(1):65-83. doi: 10.1016/j.kint.2023.09.014. Epub 2023 Sep 28.



Carolina da Cruz Junho

He et al. (2023)

“Interaction between neutrophil extracellular traps and cardiomyocytes contributes to atrial fibrillation progression.”

Signal Transduct Target Ther. 2023 Jul 26;8(1):279. doi: 10.1038/s41392-023-01497-2.



Corinna Schulte

Li et al. (2023)

“Inhibition of fatty acid oxidation enables heart regeneration in adult mice.”

Nature. 2023 Oct;622(7983):619-626. doi: 10.1038/s41586-023-06585-5. Epub 2023 Sep 27.



Dustin Mikolajetz

Nitz et al. (2022)

“The Amino Acid Homoarginine Inhibits Atherogenesis by Modulating T-Cell Function.”

Circ Res. 2022 Sep 30;131(8):701-712. doi: 10.1161/CIRCRESAHA.122.321094. Epub 2022 Sep 14.


Erik Merckelbach

Yoon et al. (2023)

“A parathyroid hormone/salt-inducible kinase signaling axis controls renal vitamin D activation and organismal calcium homeostasis.”

J Clin Invest. 2023 May 1;133(9):e163627. doi: 10.1172/JCI163627.



Julia Wollenhaupt

Soranno et al. (2022)

“Female and male mice have differential longterm cardiorenal outcomes following a matched degree of ischemia–reperfusion acute kidney injury.”

Sci Rep. 2022 Jan 12;12(1):643.doi: 10.1038/s41598-021-04701-x.



Leonida Rakateli

Snarski et al. (2022)

“Macrophage-Specific IGF-1 Overexpression Reduces CXCL12 Chemokine Levels and Suppresses Atherosclerotic Burden in Apoe-Deficient Mice.”

Arterioscler Thromb Vasc Biol. 2022 Feb;42(2):113-126. doi: 10.1161/ATVBAHA.121.316090. Epub 2021 Dec 2.



Li Zhang

Tombor et al. (2021)

“Single cell sequencing reveals endothelial plasticity with transient mesenchymal activation after myocardial infarction.”

Nat Commun. 2021 Jan 29;12(1):681.doi: 10.1038/s41467-021-20905-1.



Nicolas Hense

Zhai et al. (2022)

“Extracellular traps from activated vascular smooth muscle cells drive the progression of atherosclerosis.”

Nat Commun. 2022 Dec 6;13(1):7500.doi: 10.1038/s41467-022-35330-1.


Rosanna Huchzermeier

He et al. (2023)

“Reactive oxygen species (ROS)-responsive size-reducible nanoassemblies for deeper atherosclerotic plaque penetration and

enhanced macrophage-targeted drug delivery.”

Bioact Mater. 2022 Apr 7;19:115-126.doi: 10.1016/j.bioactmat.2022.03.041. eCollection 2023 Jan.



Michaela Lellig

Tain et al. (2023)

“Dietary Resveratrol Butyrate Monoester Supplement Improves Hypertension and

Kidney Dysfunction in a Young Rat Chronic Kidney Disease Model.”

Nutrients. 2023 Jan 26;15(3):635.doi: 10.3390/nu15030635.



Sonja Vondenhoff

Schunk et al. (2021)

“Interleukin-1α Is a Central Regulator of Leukocyte-Endothelial Adhesion in Myocardial Infarction and in Chronic Kidney Disease.”

Circulation. 2021 Sep 14;144(11):893-908. doi: 10.1161/CIRCULATIONAHA.121.053547. Epub 2021 Jul 1.

Tianyu Xia
Florens et al. (2023)
“Interleukin-33 Mediates Cardiomyopathy After Acute Kidney Injury by Signaling to Cardiomyocytes.”
Circulation. 2023 Feb 28;147(9):746-758. doi: 10.1161/CIRCULATIONAHA.122.063014. Epub 2023 Jan 25.

Tim Caspers

Li Li et al. (2023)

“Proteomic landscape of the extracellular matrix in the fibrotic kidney.”
Kidney Int. 2023 Jun;103(6):1063-1076. doi: 10.1016/j.kint.2023.01.021. Epub 2023 Feb 17.

Sanne Maas

Janssen et al. (2023)
“Monocytes re-enter the bone marrow during fasting and alter the host response to infection.”
Immunity. 2023 Apr 11;56(4):783-796.e7. doi: 10.1016/j.immuni.2023.01.024. Epub 2023 Feb 23.


Naresh Ganesh

Zhao et al. (2023)

“Heart–gut microbiota communication determines the severity of cardiac injury after myocardial ischaemia/reperfusion.”

Cardiovasc Res. 2023 Jun 13;119(6):1390-1402. doi: 10.1093/cvr/cvad023.


Sofia De la Puente Secades

Shoji et al. (2021)

„Comparative Effects of Etelcalcetide and Maxacalcitol on Serum Calcification Propensity in Secondary

Hyperparathyroidism: A Randomized Clinical Trial.”

Clin J Am Soc Nephrol. 2021 Apr 7;16(4):599-612.


Shruti Bhargava

Chen et al. (2022)

“Influence of the microbiome, diet and genetics on inter-individual variation in the human plasma metabolome.”

Nat Med. 2022 Nov;28(11):2333-2343. doi: 10.1038/s41591-022-02014-8. Epub 2022 Oct 10.


Xiyang Liu

Goldspink et al. (2023)

“Kidney medullary sodium chloride concentrations induce neutrophil and monocyte extracellular

DNA traps that defend against pyelonephritis in vivo.”

Kidney Int. 2023 Aug;104(2):279-292. doi: 10.1016/j.kint.2023.03.034. Epub 2023 Apr 23.


Burcu Yesilyurt

Shi et al. (2022)

“Oxidative phosphorylation promotes vascular calcification in chronic kidney disease.”

Cell Death Dis. 2022 Mar 11;13(3):229. doi: 10.1038/s41419-022-04679-y.


Yingying Gao

Melica et al. (2022)

“Differentiation of crescent-forming kidney progenitor cells into podocytes attenuates severe glomerulonephritis in mice.”

Sci Transl Med. 2022 Aug 10;14(657):eabg3277. doi: 10.1126/scitranslmed.abg3277. Epub 2022 Aug 10.


Zhuangting Rao

Li et al. (2022)

“An exercise-inducible metabolite that suppresses feeding and obesity.”

Nature. 2022 Jun;606(7915):785-790. doi: 10.1038/s41586-022-04828-5. Epub 2022 Jun 15.


Zhuojun Wu

Amaya- Garrido et al. (2023)

“Calprotectin is a contributor to and potential therapeutic target for vascular calcification in chronic kidney disease.”

Sci Transl Med. 2023 Sep 6;15(712):eabn5939.



Sai Sahana Sundararaman

Wang et al. (2021)

“Macrophage membrane functionalized biomimetic nanoparticles for targeted anti-atherosclerosis applications.”

Theranostics. 2021 Jan 1;11(1):164-180.doi: 10.7150/thno.47841.eCollection 2021.



Sanne Lidewij Maas

Zhang et al. (2019)

“Genetic programming of macrophages to perform anti-tumor functions using targeted mRNA nanocarriers.”

Nat Commun. 2019 Sep 3;10(1):3974.doi: 10.1038/s41467-019-11911-5.



Sofia De la Puente Secades

Chen et al. (2021)

“Naturally occurring UBIAD1 mutations differentially affect menaquinone biosynthesis and vitamin K-dependent carboxylation.”

FEBS J. 2021 Nov 23.doi: 10.1111/febs.16291.Online ahead of print.



Valeria Saar-Kovrov

Gaul et al. (2021)

“Extracellular NLRP3 inflammasome particles are internalized by human coronary artery smooth muscle cells

and induce pro-atherogenic effects.”

Sci Rep. 2021 Jul 26;11(1):15156.doi: 10.1038/s41598-021-94314-1.

Vytautas Kucikas
De Kort et al. (2021)

“Inflammatory and regenerative processes in bioresorbable synthetic pulmonary valves

up to two years in sheep–Spatiotemporal insights augmented by Raman microspectroscopy.”

Acta Biomater. 2021 Nov;135:243-259.  doi: 10.1016/j.actbio.2021.09.005.  Epub 2021 Sep 10.


Setareh Orth-Alampour
Speer et al. (2014)

“Carbamylated low-density lipoprotein induces endothelial dysfunction.”

Eur Heart J. 2014 Nov 14;35(43):3021-32.  doi: 10.1093/eurheartj/ehu111.  Epub 2014 Mar 21.


Shruti Bhargava
Freise et al. (2021)

“Uraemic extracellular vesicles augment osteogenic transdifferentiation of

vascular smooth muscle cells via enhanced AKT signalling and PiT-1 expression.”

J Cell Mol Med. 2021 Jun;25(12):5602-5614.  doi: 10.1111/jcmm.16572.  Epub 2021 May 7.

Zhoujun Wu
Nakano et al. (2019)
“Uremic Toxin Indoxyl Sulfate Promotes Proinflammatory Macrophage Activation Via the Interplay of OATP2B1 and Dll4-Notch Signaling.”
Circulation. 2019 Jan 2;139(1):78-96.  doi: 10.1161/CIRCULATIONAHA.118.034588.

Alexandra Kindelan Lohse
Kaschina et al. (2008)
“Angiotensin II type 2 receptor stimulation: a novel option of therapeutic interference with

the renin-angiotensin system in myocardial infarction?.”
Circulation. 2008 Dec 9;118(24):2523-32.  doi:10.1161/CIRCULATIONAHA.108.784868. Epub 2008 Nov 24.

Andrea Bonnin-Marquez
Busnelli et al. (2022)
“Lack of ApoA-I in ApoEKO Mice Causes Skin Xanthomas, Worsening of Inflammation,

and Increased Coronary Atherosclerosis in the Absence of Hyperlipidemia.”
Arterioscler Thromb Vasc Biol. 2022 May 19;101161ATVBAHA122317790. doi: 10.1161/ATVBAHA.122.317790.  Online ahead of print.

Constance Baaten
Kaiser et al. (2022)
“Procoagulant platelet sentinels prevent inflammatory bleeding through GPIIBIIIA and GPVI.”
Blood. 2022 Apr 26;blood.2021014914.  doi: 10.1182/blood.2021014914.  Online ahead of print.

Dustin Mikolajetz
Bogdanova et al. (2019)
“Interstitial cells in calcified aortic valves have reduced differentiation potential and stem cell-like properties.”
Sci Rep. 2019 Sep 10;9(1):12934.  doi: 10.1038/s41598-019-49016-0.

Corinna Schulte
Lin et al. (2022)
“TREM‐2 mediates dendritic cell–induced NO to suppress Th17 activation and ameliorate chronic kidney diseases.”
J Mol Med (Berl). 2022 Jun;100(6):917-931. doi: 10.1007/s00109-022-02201-7.  Epub 2022 May 9.



Melina Stein

Di Pietro et al. (2022)

“Targeting the ASMase/S1P pathway protects from sortilin - evoked vascular damage in hypertension.”

J Clin Invest. 2022 Feb 1;132(3):e146343.  doi: 10.1172/JCI146343.


Erik Merckelbach

Lim et al. (2020)

“Activation of β-catenin by TGF-β1 promotes ligament-fibroblastic differentiation and inhibits cementoblastic differentiation of human periodontal ligament cells.”

Stem Cells. 2020 Sep 15.doi: 10.1002/stem.3275.



Josefin Soppert

Lim et al. (2020)

“Gut-dependent microbial translocation induces inflammation and cardiovascular events after ST-elevation myocardial infarction.”

Microbiome. 2018 Apr 3;6(1):66.doi: 10.1186/s40168-018-0441-4.



Giulia Ilaria Bagarolo

He et al. (2021)

“Urinary peptides in heart failure: a link to molecular pathophysiology.”

Eur J Heart Fail. 2021 Nov;23(11):1875-1887.doi: 10.1002/ejhf.2195.Epub 2021 May 7.


Lea Herkens

Chang et al. (2022)

“Angiopoietin-2 inhibition attenuates kidney fibrosis by hindering chemokine C-C motif ligand 2 expression and apoptosis of endothelial cells.

Kidney Int. 2022 Oct;102(4):780-797. doi: 10.1016/j.kint.2022.06.026.Epub 2022 Aug 4.



Maren Gesper

Xue et al. (2022)

“Gut Microbially Produced Indole-3-Propionic Acid Inhibits Atherosclerosis by Promoting Reverse Cholesterol Transport and

Its Deficiency Is Causally Related to Atherosclerotic Cardiovascular Disease.”

Circ Res. 2022 Aug 19;131(5):404-420. doi: 10.1161/CIRCRESAHA.122.321253.Epub 2022 Jul 27.



Linsey Peters
Finney et al. (2017)
„EphA2 Expression Regulates Inflammation and Fibroproliferative Remodeling in Atherosclerosis.“
Circulation. 2017 Aug 8;136(6):566-582. doi: 10.1161/CIRCULATIONAHA.116.026644. Epub 2017 May 9.

Maren Gesper
Li et al. (2018)
„Gut microbe-derived metabolite trimethylamine N-oxide induces cardiac hypertrophy and fibrosis.“
Lab Invest. 2019 Mar;99(3):346-357. doi: 10.1038/s41374-018-0091-y. Epub 2018 Aug 1.

Maria Chiara Arrivas
Frodermann et al. (2019)
„Exercise reduces inflammatory cell production and cardiovascular inflammation via instruction of hematopoietic progenitor cells.“
Nat Med. 2019 Nov;25(11):1761-1771. doi: 10.1038/s41591-019-0633-x. Epub 2019 Nov 7.

Sophie Kathrin Schiestel
Li et al. (2017)
„Intermittent Fasting Promotes White Adipose Browning and Decreases Obesity by Shaping the Gut Microbiota.“
Cell Metab. 2017 Oct 3;26(4):672-685.e4. doi: 10.1016/j.cmet.2017.08.019. Epub 2017 Sep 14.

Marina Augusto Heuschkel
Allapanet et al. (2020)
„Warfarin Accelerates Medial Arterial Calcification in Humans.”
Arterioscler Thromb Vasc Biol. 2020 May;40(5):1413-1419. doi: 10.1161/ATVBAHA.119.313879. Epub 2020 Feb 13.

Michaela Lellig
Ji et al. (2019)
„Alarmone Ap4A is elevated by aminoglycosideantibiotics and enhances their bactericidal activity.“
Proc Natl Acad Sci USA. 2019 May 7;116(19):9578-9585. doi: 10.1073/pnas.1822026116. Epub 2019 Apr 19.

Pascal Mann
Wang et al. (2016)
„Opposing Effects of Fasting Metabolism on Tissue Tolerance in Bacterial and Viral Inflammation.”
Cell. 2016 Sep 8;166(6):1512-1525.e12. doi: 10.1016/j.cell.2016.07.026.

Rogier Veltrop
Ikeda et al. (2020)
„Mitochondria-Rich Extracellular Vesicles From Autologous Stem Cell-Derived Cardiomyocytes Restore Energetics of Ischemic Myocardium.“
J Am Coll Cardiol. 2021 Mar 2;77(8):1073-1088. doi: 10.1016/j.jacc.2020.12.060.

Zuppinger et al. (2017)
„Characterization of cytoskeleton features and maturation status of cultured human iPSC-derived cardiomyocytes.”
Eur J Histochem. 2017 Jun 21;61(2):2763. doi: 10.4081/ejh.2017.2763.

Sai Sahana Sundararaman
Li et al. (2021)
„Calcium-sensing receptor promotes calcium oxalate crystal adhesion and renal injury in Wistar rats by promoting ROS production and

subsequent regulation of PS ectropion, OPN, KIM-1, and ERK expression.“
Ren Fail. 2021 Dec;43(1):465-476. doi: 10.1080/0886022X.2021.1881554.

Jonas Heyn
Brestoff et al. (2021)
„Intercellular Mitochondria Transfer to Macrophages Regulates White Adipose Tissue Homeostasis and Is Impaired in Obesity.“
Cell Metab. 2021 Feb 2;33(2):270-282.e8. doi: 10.1016/j.cmet.2020.11.008. Epub 2020 Dec 4.

Sebastian Maxeiner
Shi et al. (2021)
„Neutrophils can promote clotting via FXI and impact clot structure via neutrophil extracellular traps in a distinctive manner in vitro.“
Sci Rep. 2021 Jan 18;11(1):1718. doi: 10.1038/s41598-021-81268-7.

Shruti Bhargava
Cobb et al. (2021)
„Runx2 (Runt-Related Transcription Factor 2) Links the DNA Damage Response to Osteogenic Reprogramming and

Apoptosis of Vascular Smooth Muscle Cells.”
Arterioscler Thromb Vasc Biol. 2021 Apr;41(4):1339-1357. doi: 10.1161/ATVBAHA.120.315206. Epub 2020 Dec 24.

Sofia De la Puente Secades
Martinez-Moreno et al. (2017)
„High phosphate induces a pro-inflammatory response by vascular smooth muscle cells and modulation by vitamin D derivatives.”
Clin Sci (Lond). 2017 Jun 28;131(13):1449-1463. doi: 10.1042/CS20160807. Print 2017 Jul 1.

Valeria Saar-Kovrov
Furmanik et al. (2020)
„Reactive Oxygen-Forming Nox5 Links Vascular Smooth Muscle Cell Phenotypic Switching and

Extracellular Vesicle-Mediated Vascular Calcification.“
Circ Res. 2020 Sep 11;127(7):911-927. doi: 10.1161/CIRCRESAHA.119.316159. Epub 2020 Jun 22.

Anika Himmelsbach
Gu et al. (2019)
„Inhibition of acetylation of histones 3 and 4 attenuates aortic valve calcification.”
Exp Mol Med. 2019 Jul 10;51(7):1-14. doi: 10.1038/s12276-019-0272-9.

Andrea Bonnin-Marquez
Baba et al. (2020)
„CXCR4-Binding Positron Emission Tomography Tracers Link Monocyte Recruitment and Endothelial Injury in Murine Atherosclerosis.”
Arterioscler Thromb Vasc Biol. 2021 Feb;41(2):822-836. doi: 10.1161/ATVBAHA.120.315053. Epub 2020 Dec 17.

Christian Hemmers
Chung et al. (2019)
„Mitochondrial damage and activation of the STING pathway leads to renal inflammation and fibrosis.“
Cell Metab. 2019 Oct 1;30(4):784-799.e5. doi: 10.1016/j.cmet.2019.08.003. Epub 2019 Aug 29.

Constance Baaten
Lin et al. (2021)“
Establishment of a Bernard-Soulier syndrome model in zebrafish.”
Haematologica. 2021 Aug 19.doi: 10.3324/haematol.2021.278893     



Dustin Mikolajetz

Yao et al. (2021)

„Shifting osteogenesis in vascular calcification.”

JCI Insight. 2021 May 24;6(10):e143023. doi: 10.1172/jci.insight.143023.



Federica Cascone

Baldassarre et al. (2021)

“Determination of Effective Albumin in Patients With Decompensated Cirrhosis: Clinical and Prognostic Implications.”

Hepatology. 2021 Mar 12. doi: 10.1002/hep.31798.



Giulia Ilaria Bagarolo

Lemesle et al. (2020)

„Apolipoprotein Proteomic Profiling for the Prediction of Cardiovascular Death in Patients with Heart Failure.“

Proteomics Clin Appl. 2020 Nov;14(6):e2000035. doi: 10.1002/prca.202000035. Epub 2020 Sep 28.



Luis Quintana

Xin et al. (2013)

„Mending broken hearts: cardiac development as a basis for adult heart regeneration and repair.“

Nat Rev Mol Cell Biol. 2013 Aug;14(8):529-41. doi: 10.1038/nrm3619.



Jane Lauxen

Kim et al. (2017)

“Increased Neutrophil Extracellular Trap Formation in Uremia Is Associated with Chronic Inflammation and Prevalent Coronary Artery Disease.”

J Immunol Res. 2017;2017:8415179. doi: 10.1155/2017/8415179. Epub 2017 Mar 27.



Julia Wirth

O’Sullivan et al. (2019)

“Refining the Mouse Subtotal Nephrectomy in Male 129S2/SV Mice for Consistent Modeling of Progressive Kidney Disease

With Renal Inflammation and Cardiac Dysfunction”

Front Physiol. 2019 Nov 15;10:1365. doi: 10.3389/fphys.2019.01365. eCollection 2019.



Hoda Alibiglou

Petsophonsakul et al. (2021)

"Nicotine promotes vascular calcification via intracellular Ca2+-mediated, Nox5-induced oxidative stress, and extracellular

vesicle release in vascular smooth muscle cells"

Cardiovasc Res. 2021 Jul 17;cvab244. doi: 10.1093/cvr/cvab244. Online ahead of print.



Linsey Peters

Yadati et al. (2021)

“Inhibition of Extracellular Cathepsin D Reduces Hepatic Lipid Accumulation and Leads to Mild Changes in Inflammation in NASH Mice.”

Front Immunol. 2021 Jul 16;12:675535. doi: 10.3389/fimmu.2021.675535. eCollection 2021.



Maren Gesper

Shil et al. (2021)

“Artificial Sweeteners Negatively Regulate Pathogenic Characteristics of Two Model Gut Bacteria, E. coli and E. faecalis.”

Int J Mol Sci. 2021 May 15;22(10):5228. doi: 10.3390/ijms22105228.



Marina Augusto Heuschkel

Jaiswal et al. (2017)

“Clonal Hematopoiesis and Risk of Atherosclerotic Cardiovascular Disease.”

N Engl J Med. 2017 Jul 13;377(2):111-121. doi: 10.1056/NEJMoa1701719. Epub 2017 Jun 21.



Maria Chiara Arrivas

Barrett et al. (2021)

“Chronic stress primes innate immune responses in mice and humans.”

Cell Rep. 2021. PMID: 34496250



Maximilian Sausen

He et al. (2019)

“Gut intraepithelial T cells calibrate metabolism and accelerate cardiovascular disease.”

Nature. 2019 Feb;566(7742):115-119. doi: 10.1038/s41586-018-0849-9. Epub 2019 Jan 30.


Michaela Lellig

Zhang et al. (2021)

“Effects of Angiotensin II type I receptor shRNA on blood pressure and left ventricular remodeling in spontaneously hypertensive rats.”

Exp Anim. 2021 Aug 6;70(3):293-301. doi: 10.1538/expanim.20-0152. Epub 2021 Feb 11.



Nadim Tabaza

Anzai et al. (2017)

“The infarcted myocardium solicits GM-CSF for the detrimental oversupply of inflammatory leukocytes.”

J Exp Med. 2017 Nov 6;214(11):3293-3310. doi: 10.1084/jem.20170689. Epub 2017 Oct 4



Nicolas Hense

Chattopadhyay et al. (2021)

“Cholesterol-Induced Phenotypic Modulation of Smooth Muscle Cells to Macrophage/Fibroblast-like Cells Is Driven by an Unfolded Protein Response.”

Arterioscler Thromb Vasc Biol. 2021 Jan;41(1):302-316. doi: 10.1161/ATVBAHA.120.315164. Epub 2020 Oct 8.



Pascal Mann

Croteau et al. (2021)

“Effects of Sodium-Glucose Linked Transporter 2 Inhibition With Ertugliflozin

on Mitochondrial Function, Energetics, and Metabolic Gene Expression in the Presence and Absence of Diabetes Mellitus in Mice.”

J Am Heart Assoc. 2021 Jul 6;10(13):e019995. doi: 10.1161/JAHA.120.019995. Epub 2021 Jun 25.




Josefin Soppert

Pouwer et al. (2020)

“Alirocumab, evinacumab, and atorvastatin triple therapy regresses plaque lesions and improves lesion composition in mice.”

J Lipid Res. 2020 Mar;61(3):365-375. doi: 10.1194/jlr.RA119000419. Epub 2019 Dec 16.



Pascal Mann

Ho et al. (2019)

“Increased ketone body oxidation provides additional energy for the failing heart without improving cardiac efficiency.”

Cardiovasc Res. 2019 Sep 1;115(11):1606-1616. doi: 10.1093/cvr/cvz045.



Julia Wirth

Jiang et a. (2019)

“Endothelial cell modulation of cardiomyocyte gene expression.”

Exp Cell Res. 2019 Oct 15;383(2):111565. doi: 10.1016/j.yexcr.2019.111565. Epub 2019 Aug 20.



Kabita Pradhan

Zhao et al. (2018)

“Cardiomyocyte Derived miR-328 Promotes Cardiac Fibrosis by Paracrinely Regulating Adjacent Fibroblasts.”

Cell Physiol Biochem. 2018;46(4):1555-1565. doi: 10.1159/000489201. Epub 2018 Apr 19.



Katja Krüger

Oleinik et al. (2019)

“Mitochondrial protein import is regulated by p17/PERMIT to mediate lipid metabolism and cellular stress.”

Sci Adv. 2019 Sep 11;5(9):eaax1978. doi: 10.1126/sciadv.aax1978. eCollection 2019 Sep.



Linsey Peters

Negishi et al. (2008)

“A critical link between Toll-like receptor 3 and type II interferon signaling pathways in antiviral innate immunity.”

Proc Natl Acad Sci U S A. 2008 Dec 23;105(51):20446-51. doi: 10.1073/pnas.0810372105. Epub 2008 Dec 11



Mareike Staudt

Rosshart et al. (2019)

"Laboratory mice born to wild mice have natural microbiota and model human immune responses.”

Science. 2019 Aug 2;365(6452):eaaw4361. doi: 10.1126/science.aaw4361. Epub 2019 Aug 1.



Marina Augusto Heuschkel

Zhang et al. (2020)

“Trimethylamine-N-Oxide Promotes Vascular Calcification Through Activation of NLRP3 (Nucleotide-Binding Domain, Leucine-Rich-Containing Family, Pyrin Domain-Containing-3) Inflammasome and NF-κB (Nuclear Factor κB) Signals.”

Arterioscler Thromb Vasc Biol. 2020 Mar;40(3):751-765. doi: 10.1161/ATVBAHA.119.313414. Epub 2020 Jan 16.



Maria Chiara Arrivas

McAlpine et al. (2019)

“Sleep modulates haematopoiesis and protects against atherosclerosis.”

Nature. 2019 Feb;566(7744):383-387. doi: 10.1038/s41586-019-0948-2. Epub 2019 Feb 13.



Maren Gesper

Tang et al. (2019)

“Loss of Gut Microbiota Alters Immune System Composition and Cripples Postinfarction Cardiac Repair.”

Circulation. 2019 Jan 29;139(5):647-659. doi: 10.1161/CIRCULATIONAHA.118.035235.



Pascal Mann

Kim et al. (2020)

“SGLT2 inhibition modulates NLRP3 inflammasome activity via ketones and insulin in diabetes with cardiovascular disease.”

Nat Commun. 2020 May 1;11(1):2127. doi: 10.1038/s41467-020-15983-6.



Sofia de la Puente Secades

De Maré et al. (2019)

„Sclerostin as Regulatory Molecule in Vascular Media Calcification and the Bone–Vascular Axis.“

Toxins (Basel). 2019 Jul 21;11(7):428. doi: 10.3390/toxins11070428.



Sebastian Maxeiner

Wilbs et al. (2020)

„Cyclic peptide FXII inhibitor provides safe anticoagulation in a thrombosis model and in artificial lungs.“

Nat Commun. 2020 Aug 4;11(1):3890. doi: 10.1038/s41467-020-17648-w.



Shruti Bhargava

Lino et al. (2018)

„Diabetic Vascular Calcification Mediated by the Collagen Receptor Discoidin Domain Receptor 1

via the Phosphoinositide 3-Kinase/Akt/Runt-Related Transcription Factor 2 Signaling Axis.“

Arterioscler Thromb Vasc Biol. 2018 Aug;38(8):1878-1889. doi: 10.1161/ATVBAHA.118.311238.



Sai Sahana Sundararaman

Li et al. (2020)

„A novel function of calcium sensing receptor in chronic hypoxia- induced pulmonary venous smooth muscle cells proliferation.“

Hypertens Res. 2020 Apr;43(4):271-280. doi: 10.1038/s41440-019-0373-9. Epub 2019 Dec 18.



Andrea Bonnin Marquez

Gao et al. (2020)

„Treatment of atherosclerosis by macrophage- biomimetic nanoparticles via targeted

pharmacotherapy and sequestration of proinflammatory cytokines.“

Nat Commun. 2020 May 26;11(1):2622. doi: 10.1038/s41467-020-16439-7.



Andrea Himmelsbach

Zhou et al. (2020)

„HDAC1-mediated deacetylation of LSD1 regulates vascular calcification by promoting autophagy in chronic renal failure.“

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