PhD MD TRR219-associated students
University Hospital RWTH Aachen
Department of Cardiology, Medical Clinic I
Project: The role of cytoskeleton dynamics in intimal and medial calcification
PI: Claudia Goettsch
Detailed underlying mechanisms of intimal and medial vascular calcification, a main cause of cardiovascular death, remain unclear. Preliminary results show differentially expressed genes involved in the cytoskeleton of calcified vascular smooth muscle cells. This project aims to investigate the role of cytoskeleton dynamics in particular actin polymerization in in vitro intimal and medial calcification.