PhD MD TRR219-associated students
University Hospital RWTH Aachen
Institute of Experimental Medicine and Systems Biology
Project: Role of CXCL4 in kidney and cardiac fibrosis
PI: Rafael Kramann
Fibrosis is a key feature of ischemic organ injury and aggravates organ failure after myocardial infarction and acute kidney injury. We are decoding crosstalk between platelets, leukocytes and myofibroblast to better understand fibrogenesis and identify potential drug targets to preserve organ function after ischemic injury. Currently we are investigating the role of the platelet associated protein Cxcl4 on leukocyte polarization and myofibroblast differentiation."