Dr. Heidi Noels and Dr. Yvonne Döring receive the W.H. Hauss Award from the DGAF
19-21 April 2018
Dr. Heidi Noels from the Institute for Molecular Cardiovascular Research at RWTH Aachen University together with Dr. Yvonne Döring from the Institute for Prophylaxis and Epidemiology of Circulatory Diseases at LMU Munich together received the DGAF W.H. Hauss Award 2018 from the German Society for Atherosclerosis Research (DGAF) during the 32nd Annual Meeting of the DGAF in Rauischholzhausen, Germany. They were awarded for their publication "Vascular CXCR4 Limits Atherosclerosis by Maintaining Arterial Integrity: Evidence From Mouse and Human Studies." (Circulation. 2017; 136: 388-403). In this work it could be shown that vascular CXCR4 has an atheroprotective function by maintaining the arterial integrity and preserving the endothelial barrier function. In addition, CXCR4 stabilizes a contractile smooth muscle cell phenotype. Targeted enhancement of these CXCR4-mediated protective functions could open up novel therapeutic options in the treatment of atherosclerosis.
The award was sponsored by a long-standing active member of the DGAF, Prof. Dr. Winfried März.
Project area Z
Administrative project
Robert Werner Mertens
MD student
University Hospital RWTH Aachen
Department of Internal Medicine
Project: The role of incretin hormone GLP-2 in septic cardiomyopathy
PI: Michael Lehrke
Robert Werner Mertens
MD student
University Hospital RWTH Aachen
Department of Internal Medicine
Project: The role of incretin hormone GLP-2 in septic cardiomyopathy
PI: Michael Lehrke
Consortium
Mechanisms of Cardiovascular Complications
in Chronic Kidney Disease
The SFB/TRR219 is supported by the German Research Foundation (DFG)
Project-ID 322900939
On Friday-Saturday, May 4-5 2018, the kick-off meeting of the Transregional Collaborative Research Center TRR219 took place in Seeheim-Jugenheim/Hesse.
Besides lectures relating to the topic “Mechanisms of Cardiovascular Complications in Chronic Kidney Disease” by expert speakers from research, industry, politics, patient organisations and society, the participants from the Saarland University and University Hospital RWTH Aachen were offered the opportunity to exchange experiences and ideas about the ongoing projects and increase consortium cooperations.
The meeting marked the start of an initially 4-year DFG-funded cooperation of the two universities to investigate the multi-factorial aspects of chronic kidney disease-related cardiovascular morbidity and mortality.
We thank Bayer, Novo Nordisk, Boehringer Ingelheim and Sanofi for the financial support in organizing this meeting.
SFB/TRR219 cooperates with the German patient organisation for kidney disease “Bundesverband Niere e.V.”
May 4th 2018
The SFB/TRR219 consortium, funded by the German Research Foundation, has initiated a cooperation with the German patient organisation for patients with kidney disease (“Bundesverband Niere e.V.”) with the aim to create new synergies between research and the patient organisation and to increase the involvement of patients from basic research to realization of innovating therapy ideas.
This cooperation was formalized by a letter of intent signed by
-Peter Gilmer, chair of the “Selbsthilfenetzwerk Bundesverband Niere e.V.” and representing the „Patientenstiftung Aktion Niere“;
-Martin Koczor, Managing Director of the “Bundesverband Niere e.V”
-Prof. Jankowski (speaker of the SFB/TRR219 and Head of the Institute for Molecular Cardiovascular Research, RWTH Aachen);
-Prof. Fliser (vice speaker of the SFB/TRR219 and Head of the Nephrology Department, Saarland University Hospital);
-Prof. Marx (Head of the Cardiology Department RWTH Aachen University);
and Prof. Floege (Head of the Nephrology Department RWTH Aachen University).
A publication in the patient journal “der Nierenpatient” accompanied this letter of intent to enhance awareness among patients with chronic kidney disease
Professor Jürgen Floege awarded by the ERA-EDTA
Mai 2nd 2018
ERA-EDTA Award for Outstanding Clinical Contributions to Nephrology
Professor Jürgen Floege, PI of subproject C-1 and member of the SFB/TRR219 Executive Board received the "ERA-EDTA Award for Outstanding Clinical Contributions to Nephrology".
Girls' Day
April 26th 2018, University Aachen
Girls’ Day supported by SFB-TRR219
On the 26th of April 2018, the Girls’ Day took place for the first time at the Institute for
Molecular Cardiovascular Research (IMCAR), University Clinic Aachen.
Robert Mertens receives the Gotthard-Schettler-Prize from the DGAF
19-21 April 2018
Robert Mertens of the Cardiology Department, University of Aachen, received the Gotthard-Schettler-Prize at the 32nd Annual Meeting of the German Society for Atherosclerosis Research (DGAF)in Rauischholzhausen, Germany. This prize for the best ‘Young Scientist Oral Presentation’ was awarded for his excellent talk on “The incretin hormone GLP-2 is secreted from pancreatic alpha cells during acute inflammation through IL-6 and protects against septic cardiomyopathy and shock”.
Robert Mertens is cand. med. within the graduate school of the SFB/TRR219, supervised by PD Dr. Michael Lehrke.
Dr. Heidi Noels and Dr. Yvonne Döring receive the W.H. Hauss Award from the DGAF
19-21 April 2018
Dr. Heidi Noels from the Institute for Molecular Cardiovascular Research at RWTH Aachen University together with Dr. Yvonne Döring from the Institute for Prophylaxis and Epidemiology of Circulatory Diseases at LMU Munich together received the DGAF W.H. Hauss Award 2018 from the German Society for Atherosclerosis Research (DGAF) during the 32nd Annual Meeting of the DGAF in Rauischholzhausen, Germany. They were awarded for their publication "Vascular CXCR4 Limits Atherosclerosis by Maintaining Arterial Integrity: Evidence From Mouse and Human Studies." (Circulation. 2017; 136: 388-403). In this work it could be shown that vascular CXCR4 has an atheroprotective function by maintaining the arterial integrity and preserving the endothelial barrier function. In addition, CXCR4 stabilizes a contractile smooth muscle cell phenotype. Targeted enhancement of these CXCR4-mediated protective functions could open up novel therapeutic options in the treatment of atherosclerosis.
The award was sponsored by a long-standing active member of the DGAF, Prof. Dr. Winfried März.
The new SFB/TRR219 Research Centre
March 21st 2018
SFB TRR219 Concept Paper in Eur Heart J published
A new Transregional Collaborative Research Center of the German Research Foundation (DFG) has been created to address reno-cardiovascular interactions underlying the increased cardiovascular risk in patients with chronic kidney disease to develop novel treatment strategies to reduce cardiovascular morbidity and mortality in these high-risk patients.
LAB TASTER DAYS
13 March 2018, University Aachen
Molecular biological research in Medicine
On the 13th of March 2018, a trial day for young students interested in doing research took once again place at the Institute for Molecular Cardiovascular Research (IMCAR), University Clinic Aachen.
Students from grades 10-13 (age 15-18) were invited to the Institute under the motto:
"Molecular biology research in medicine: sounds interesting, but what is it?"
First joint student workshop - Marie-Curie ITN INTRICARE and IRTG TRR219 in Aachen
6th March 2018
The first network-wide training of the TRR219 graduate school together with the ITN INTRICARE was
held in March 2018 in Aachen. Scientist from the training grants and invited speakers gave exciting
lectures on key topics, like vascular imaging; calcification of bone and vessels; bioanalytics; clinical
challenges in patients with chronic kidney disease and diabetes.
.