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Dr. Heidi Noels and Dr. Yvonne Döring receive the W.H. Hauss Award from the DGAF

19-21 April 2018

Dr. Heidi Noels from the Institute for Molecular Cardiovascular Research at RWTH Aachen University together with Dr. Yvonne Döring from the Institute for Prophylaxis and Epidemiology of Circulatory Diseases at LMU Munich together received the DGAF W.H. Hauss Award 2018 from the German Society for Atherosclerosis Research (DGAF) during the 32nd Annual Meeting of the DGAF in Rauischholzhausen, Germany. They were awarded for their publication "Vascular CXCR4 Limits Atherosclerosis by Maintaining Arterial Integrity: Evidence From Mouse and Human Studies." (Circulation. 2017; 136: 388-403). In this work it could be shown that vascular CXCR4 has an atheroprotective function by maintaining the arterial integrity and preserving the endothelial barrier function. In addition, CXCR4 stabilizes a contractile smooth muscle cell phenotype. Targeted enhancement of these CXCR4-mediated protective functions could open up novel therapeutic options in the treatment of atherosclerosis.

The award was sponsored by a long-standing active member of the DGAF, Prof. Dr. Winfried März.

Project area Z

Administrative project

Robert Werner Mertens

MD student

University Hospital RWTH Aachen

Department of Internal Medicine

Project: The role of incretin hormone GLP-2 in septic cardiomyopathy

PI: Michael Lehrke

Robert Werner Mertens

MD student

University Hospital RWTH Aachen

Department of Internal Medicine

Project: The role of incretin hormone GLP-2 in septic cardiomyopathy

PI: Michael Lehrke

Consortium

Summerschool 2018

Mechanisms of Cardiovascular Complications

in Chronic Kidney Disease

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The SFB/TRR219 is supported by the German Research Foundation (DFG)

Project-ID 322900939

Konrad Hoeft and Lars Koch awarded the „Paper of the month“ award

SFB/TRR219
Jan 15
1 min read

In January, Konrad Hoeft and Lars Koch, PostDoc resp. Dr med. student in SFB/TRR29 project C-05 (Kramann), were awarded the „Paper of the Month“ award of the Medical Faculty, RWTH University of Aachen.

The investigated the role of the enzyme ADAMTS12 in fibrosis in kidney and heart, as well as strategies to prevent such detrimental tissue fibrosis. Their paper, titled " ADAMTS12 promotes fibrosis by restructuring extracellular matrix to enable activation of injury-responsive fibroblasts" was published in J Clin Invest:

https://pubmed.ncbi.nlm.nih.gov/39286973

Congratulations Konrad and Lars!

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