FGF23 is a protein mainly produced in osteocytes and acting on the kidney to regulate phosphate homeostasis and vitamin D metabolism. It has recently been shown to be directly correlated with cardiovascular mortality after myocardial infarction. However, the role of FGF23 in remodeling processes after acute myocardial infarction is still unknown.

​

We investigate the local role and function of FGF23 in a mouse model of myocardial infarction induced by left anterior descending artery ligation.