PhD MD TRR219-associated students
Marieke Sternkopf
PhD student
University Hospital RWTH Aachen
Institute for Molecular Cardiovascular Research
Project: From the pathophysiology of cardiovascular disease to new therapeutic approaches
PI: Heidi Noels
Thrombotic microangiopathies (TMA) are rare diseases associated with poor prognosis, which often lead to chronic kidney disease (CKD) with respective consequences. PDGF stimulates the formation of fibrosis in CKD, but also promotes the regeneration of endothelial cells. The aim of this study is to investigate the potential dual role of PDGF in an animal model of TMA.