PhD MD TRR219-associated students
University Hospital RWTH Aachen
Institute for Molecular Cardiovascular Research
Project: Interaction of platlets and vasculature in thrombus formation in chronic kidney disease.
PI: Heidi Noels
Microcalcification associates with reduce atherosclerotic plaque integrity and may trigger rupture. Tissue non-specific alkaline phosphatase (TNAP) is a key enzyme in the calcification process. The main objective of this study is to determine the molecular mechanisms that are involved in TNAP maturation and activation.