Dr. Heidi Noels and Dr. Yvonne Döring receive the W.H. Hauss Award from the DGAF
19-21 April 2018
Dr. Heidi Noels from the Institute for Molecular Cardiovascular Research at RWTH Aachen University together with Dr. Yvonne Döring from the Institute for Prophylaxis and Epidemiology of Circulatory Diseases at LMU Munich together received the DGAF W.H. Hauss Award 2018 from the German Society for Atherosclerosis Research (DGAF) during the 32nd Annual Meeting of the DGAF in Rauischholzhausen, Germany. They were awarded for their publication "Vascular CXCR4 Limits Atherosclerosis by Maintaining Arterial Integrity: Evidence From Mouse and Human Studies." (Circulation. 2017; 136: 388-403). In this work it could be shown that vascular CXCR4 has an atheroprotective function by maintaining the arterial integrity and preserving the endothelial barrier function. In addition, CXCR4 stabilizes a contractile smooth muscle cell phenotype. Targeted enhancement of these CXCR4-mediated protective functions could open up novel therapeutic options in the treatment of atherosclerosis.
The award was sponsored by a long-standing active member of the DGAF, Prof. Dr. Winfried März.
Project area Z
Administrative project
Robert Werner Mertens
MD student
University Hospital RWTH Aachen
Department of Internal Medicine
Project: The role of incretin hormone GLP-2 in septic cardiomyopathy
PI: Michael Lehrke
Robert Werner Mertens
MD student
University Hospital RWTH Aachen
Department of Internal Medicine
Project: The role of incretin hormone GLP-2 in septic cardiomyopathy
PI: Michael Lehrke
Consortium
Mechanisms of Cardiovascular Complications
in Chronic Kidney Disease
The SFB/TRR219 is supported by the German Research Foundation (DFG)
Project-ID 322900939
TRR219-funded group
Eva Harlacher
PhD student
University Hospital RWTH Aachen
Institute for Molecular Cardiovascular Research
Project M-05: Inflammatory mediators linking CKD to adverse cardiac remodeling after myocardial infarction
PI: Heidi Noels, Nikolaus Marx
Burcu Yesilyurt
PhD student
University Hospital RWTH Aachen
Institute of Pathology - Medical Clinic II
Project M-01: Platelet-Derived Growth Factor (PDGF) – a mediator of Cardiovascular Diseases in Chronic Kidney Disease
PI: Peter Boor; Jürgen Floege
Julia Wirth
PhD student
University Hospital RWTH Aachen
Institute for Molecular Cardiovascular Research
Project M-05: Inflammatory mediators linking CKD to adverse cardiac remodeling after myocardial infarction
PI: Heidi Noels, Nikolaus Marx
Juliane Hermann
PhD student
University Hospital RWTH Aachen
Institute for Molecular
Cardiovascular Research
Project S-03: Mass spectrometry to identify novel regulators of pathological processes underlying CKD-associated CVD
PI: Vera Jankowski /Joachim Jankowski
Andrea Büscher
PhD student
University Hospital RWTH Aachen
Institute for Biomedical Engineering - Biointerface Laboratory
Project C-03: The pathophysiology of lipidic calcified particles in CKD
PI: Wilhelm Jahnen-Dechent
Anika Himmelsbach
PhD student
University Hospital RWTH Aachen
Department of Cardiology, Medical Clinic I
Project C-02: The role of the VPS10 domain receptor family in cardiovascular calcification in CKD
PI: Claudia Goettsch
Katja Krüger
PhD Student
University Hospital RWTH Aachen
Department of Cardiology, Medical Clinic I
Project M-03: Metabolic and mitochondrial dysregulation in uremic cardiomyopathy
PI: Michael Lehrke
Michaela Lellig
PhD student
University Hospital RWTH Aachen
Institute for Molecular Cardiovascular Research
Project S-03: Mass spectrometry to identify novel regulators of pathological processes underlying CKD-associated CVD
PI: Vera Jankowski/
Joachim Jankowski