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Welcome to SFB Evaluation

Vorantrag/Pre-application

Publications within pre-application:

accepted but not yet online available in revision or submitted

C-01 Floege

Terhuerne J, van Diepen M, Kramann R, Erpenbeck J, Dekker F, Marx N, Floege J, Schlieper G. Speckle tracking Echocardiography for prediction of cardiovascular mortality in patients with End Stage Renal Disease. Clin Kidney J (Accepted).

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C-04 Jankowski J

Orth-Alampour S, Gayrard N, Salem S, Bhargava S, Jankowski V, Jover, Notarnicola C, Noels H, P.C. van der Vorst E, Theelen W, Bruck H, Fliser D, Loscalzo J, Wu Z, Marx N; Zidek W, Argiles A, Jankowski J.

Inhibition of osteogenic transdifferentiation by an endogenous mediator for the prevention of vascular calcification.

Eur Heart J (in revision). Read

Jankowski J, Floege J., Fliser D, Böhm M., Marx N.

Cardiovascular disease in chronic kidney disease: pathophysiological insights and therapeutic options Circulation 2021 (Accepted). Read

Noels H, Lehrke M, Vanholder R, Jankowski J.

Lipoproteins and fatty acids in CKD: from molecular and meta-bolic alterations to pathophysiology and risk for kidney and heart. Nature review nephrology (Accepted). Read

R. Vanholder , A. Argiles, J Jankowski for the European Uremic Toxin Work Group (EUTox)

A history of uremic toxicity and of the European Uremic Toxin Work Group (EUTox) Read

C-06 Van der Vorst/Kahles

Kahles F, Mertens RW, Rückbeil MV, Arrivas MC, van der Vorst EPC, Moellmann J, Lebherz C, Biener M, Giannitsis E, Katus HA, Marx N, Lehrke M.

The gut hormone GLP-2 is associated with cardiovascular risk in patients with myocardial infarction. (in preparation). Read

Sundararaman SS, Peters LJ, Jansen Y, Gencer S, Yan Y, Nazir S, Bonnin- Marquez A, Kahles F, Lehrke M, Biessen EA, Jankowski J, Weber C, Döring Y, Van der Vorst EPC. Adipocyte Calcium Sensing Receptor is not involved in in-vivo visceral adipose tissue inflammation or atherosclerosis development in hyperlipidemic Apoe-/- mice. Scientific Reports. (in revision). Read

C-08 Speer

Schunk SJ; Ampofo E, Triem S, Sarakpi T, Becker E, Hütter G, Hohl M, Alansary D, Prates-Roma L, Lipp P, Möllmann J, Lehrke M, Laschke MW, Menger MD, Kramann R, Boor P, Göttsch C, Laufs U, Marx N, Niemeyer BA, Fliser D, Speer T. T Interleukin-1 a is a central regulator of inflammation in cardiovascular and kidney diseases. (in revision). Read

Schunk SJ, Beisswenger C, Ritzmann F, Herr C, Wagner M, Triem S, Hütter G, Schmit D, Zewinger S, Sarakpi T, Honecker A, Boor P, Jörres R, Watz H, Welte T, Vogelmeier CF, Fliser D, Bals R, Speer T. Urinary Dickkopf-3 (DKK3) uncovers inapparent progressive kidney injury: an observational study and experimental validation. (in revision). Read

Schunk SJ, Hermann J, Triem S, Sarakpi T, Lellig M, Hahm E, Zewinger S, Möllmann J, Lehrke M, Kramann R, Boor B, Lipp P, Laufs U, Reiser J, Jankowski J, Fliser D, Speer T, Jankowski V. Guanidinylated apolipoprotein C3 (ApoC3) causes cardiovascular and kidney injury. (in revision). Read

C-09 Schunk/Fliser

Schunk SJ, Kleber MK, März W, Pang S, Zewinger S, Triem S, Ege P, Reichert MC, Krawczyk K, Weber SN, Jaumann I, Schmit D, Sarakpi T, Wagenpfeil S, Kramann R, Boerwinkle E, Ballantyne CM, Grove-Gaona ML, Tragante V, Pilbrow AP, Richards AM, Cameron VA, Doughty RN, Dubé MP, Tardif JC, Feroz-Zada Y, Sun M, Liu C, Ko YA, Quyyumi AA, Hartiala JA, Tang WHW, Hazen SL, Allayee HA, McDonough CW, Gong Y, Cooper-DeHoff RM, Johnson JA, Scholz M, Teren A, Burkhardt R, Martinsson A, Smith JG, Wallentin L, James AK, Eriksson N, White H, Held C, Waterworth D, Trompet S, Jukema JW, Ford I, Stott DJ, Sattar N, Cresci S, Spertus JA, Campbell H, eQTLGen consortium, BIOS consortium, Tierling S, Walter J, Ampofo E, Niemeyer BA, Lipp P, Schunkert H, Böhm M, Lammert L, Koenig W, Fliser D, Laufs U, Speer T. Genetically-determined NLRP3 inflammasome activation associates with systemic inflammation and cardiovascular mortality. Eur Heart J. (Accepted). Read

M-02 Hohl/Böhm

Selejan SR, Linz D, Hohl M, Tatu AM, Markwirth P, Speer T, Jankowski J, Kazakov A, Werner C, Mahfoud F, Böhm M. Renal denervation improves renal remodelling and function in a model for hypertension and metabolic syndrome - role of RAGE/sRAGE balance. (Submitted). Read

Selejan SR, Linz D, Hohl M, Huynh AKD, Mautz M, Wintrich J, Kazakov A, Werner C, Mahfoud F, Böhm M. Renal denervation reduces atrial remodeling in hypertensive rats with metabolic syndrome. (Submitted). Read

Selejan SR, Linz D, Hohl M, Dederer J, Kazakov A, Zamyatkin O, Lauder L, Speer T, Krawczyk M, Lammert F, Mahfoud F, Böhm M. Effects of sympathetic modulation by renal denervation on hepatosteatosis and liver RAGE/sRAGE balance. (Submitted). Read

Selejan SR, Khoshkish S, Zamyatkin O, Hohl M, Kazakov A, Ewen S, Bachelier K, Klingel K, Wagenpfeil S, Böhm M, Kindermann I. Differentiation of inflammatory cardiomyopathy from non-inflammatory cardiomyopathy by circulating High Mobility Group Box 1 protein. (Submitted). Read

M-03 Lehrke/Marx

Marx N, Floege J. Dapagliflozin, advanced chronic kidney disease and mortality: new insights from the DAPA-CKD trial. Eur Heart J. 2021; (in press). Read

M-04 Roma/Niemeyer/Speer

Ramesh G, Jarzembowski L, Schwarz Y, Konrad M, Poth V, Schwär G, Lauer AA, Grimm MOW, Alansary D, Bruns D, Niemeyer BA: Short STIM1B uncovers a mechanism of synaptic enhancement. Cell Reports 2021. (Accepted). Read

Schunk SJ, Kleber MK, März W, Pang S, Zewinger S, Triem S, Ege P, Reichert MC, Krawczyk K, Weber SN, Jaumann I, Schmit D, Sarakpi T, Wagenpfeil S, Kramann R, Boerwinkle E, Ballantyne CM, Grove-Gaona ML, Tragante V, Pilbrow AP, Richards AM, Cameron VA, Doughty RN, Dubé MP, Tardif JC, Feroz-Zada Y, Sun M, Liu C, Ko YA, Quyyumi AA, Hartiala JA, Tang WHW, Hazen SL, Allayee HA, McDonough CW, Gong Y, Cooper-DeHoff RM, Johnson JA, Scholz M, Teren A, Burkhardt R, Martinsson A, Smith JG, Wallentin L, James AK, Eriksson N, White H, Held C, Waterworth D, Trompet S, Jukema JW, Ford I, Stott DJ, Sattar N, Cresci S, Spertus JA, Campbell H, eQTLGen consortium, BIOS consortium, Tierling S, Walter J, Ampofo E, Niemeyer BA, Lipp P, Schunkert H, Böhm M, Lammert L, Koenig W, Fliser D, Laufs U, Speer T. Genetically-determined NLRP3 inflammasome activation associates with systemic inflammation and cardiovascular mortality. Eur Heart J. 2021. (Accepted). Read

M-05 Noels/Marx

Jankowski J, Floege J, Fliser D, Böhm M, Marx N. Cardiovascular disease in chronic kidney disease: pathophysiological insights and therapeutic options. Circulation 2021. (Accepted). Read

Noels H, Lehrke M, Vanholder R., Jankowski J. Lipoproteins and fatty acids in CKD: from molecular and metabolic alterations to pathophysiology and risk for kidney and heart. Nature Nephrology Reviews 2021. (Accepted). Read

M-06 Werner

Selejan SR, Linz D, Hohl M, Tatu AM, Markwirth P, Speer T, Jankowski J, Kazakov A, Werner C, Mahfoud F, Böhm M. Renal denervation improves renal remodelling and function in a model for hypertension and metabolic syndrome-role of RAGE/sRAGE balance. Kidney International (submitted). Read

Selejan SR, Linz D, Hohl M, Huynh D, Mauz M, Wintrich J, Kazakov A, Werner C, Mahfoud F, Böhm M. Renal denervation reduces atrial remodelling in hypertensive rats with metabolic syndrome. Basic Research in Cardiology (submitted). Read

S-03 Jankowski V/Jankowski J

Jankowski J., Floege J., Fliser D, Böhm M., Marx N. Cardiovascular disease in chronic kidney disease: pathophysiological insights and therapeutic options Circulation 2021 (Accepted). Read

Noels H, Lehrke M, Vanholder R, Jankowski J. Lipoproteins and fatty acids in CKD: from molecular and meta-bolic alterations to pathophysiology and risk for kidney and heart. Nature review nephrology (Accepted). Read

Wu Z, van der Vorst EPC, Jankowski V*, Jankowski J*. Irreversible post-translational modifications: Cardiovascular risk factors and avenue for therapy. Trend in Molecular Medicine *shared last authorship (Submitted). Read

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