The 3nd TRR219 Workshop took place from 18-19 October in Homburg. In seminars and ‘hands-on’ sessions, TRR219 students extended their knowledge on the topics of inflammation and oxidative stress. Dr. Dr. T. Speer gave exciting insights into the basic principles of inflammation and the innate immune system. The practical training included isolation techniques of human peripheral blood monocytes. Jun. Prof. Dr. L. Prates-Roma provided insights into the basics and methods for studying the cellular redox state. The application of genetically-encoded redox sensors to identify redox changes in different cellular compartments in living cells was taught in the practical class. A team building social activity included a hike to the Schlossberghöhlen and a dinner in good spirits.